Flies put the buzz back into long-term-potentiation
نویسندگان
چکیده
منابع مشابه
P19: Long-Term Potentiation
The term synaptic plasticity points to a series of persistent changes related to the activity of synapses. Long-term potentiation (LTP) is a reflection of synaptic plasticity that has an important role in learning and memory. LTP is a long-lasting increase of synaptic activity due to enhancement of excitatory synaptic transmission after a high-frequency train of electrical stimulations. Differe...
متن کاملP18: Signaling Pathway in Long-Term Potentiation
Synaptic plasticity in the central nervous system (CNS) of mammals has been discussed for many years. Several forms of synaptic plasticity of mammal’s CNS have been identified, such as those that occur in long-term potentiation (LTP). Different types of LTP have been observed in distinctive areas of the CNS of mammals. The hippocampus is one of the most important areas in the CNS that pla...
متن کاملBlock of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation
The effect of endogenous serotonin on long-term potentiation (LTP) in region CAI was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly en-hanced long-term potentiation of the CAI population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CAI...
متن کاملP13: Potassium Channels and Long-Term Potentiation Formation
Long-term potentiation (LTP) is a form of activity-dependent plasticity that occurs during learning. Potassium channels are the most diverse group of all ion channels that related to synaptic plasticity. Small-conductance calcium-activated potassium channels (SKs) are found in hippocampal CA1 neurons and by inhibiting of postsynaptic potentials are involved in synaptic transmission impairment. ...
متن کاملLong-Term Potentiation
Long-term potentiation (LTP) is a long-lasting strengthening of synaptic transmission that is triggered by brief periods of high-frequency synaptic stimulation. Other patterns of stimulation can produce a long-term weakening of synapses, a process termed long-term depression (LTD) or depotentiation. Synapses thus have a stable strength that can be bi-directionally modified in an activity-depend...
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ژورنال
عنوان ژورنال: Nature Neuroscience
سال: 2002
ISSN: 1097-6256,1546-1726
DOI: 10.1038/nn0402-289